| Catalog No. : | PJK-1791 | ||||||||||
| Product Name : | Acetal-NHS (SDMB),C14H15NO6 | ||||||||||
| Description : | Acetal-NHS is a short linker without PEG providing both acetal and NHS functional groups. SDMB is the short name for this short linker acetal-NHS. SDMB stands for Succininimidyl 4-(DimethoxyMethyl)Benzoate, CAS No. 120465-57-8. First, amino /amine groups react with the NHS ester group of Acetal-NHS, yielding a stable amidebond. next, the acetal function is hydrolyzed into an aldehyde group by use ofaqueous acid such as citric acid. Next, the aldehyde group reacts with another amino group of proteins or other molecules, yielding a semi-permanent C=N bond, which can be instantaneously converted into a stable CH−NH bond by NaCNBH3. References: 1.Linking of Sensor Molecules with Amino Groups to Amino-Functionalized AFM Tips, Bioconjugate Chem., 2011, 22 (6), pp 1239–1248, Text. Click hereto view an expanded list of hundreds of publications citing Creative PEGWorks products. | ||||||||||
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